Our Focus

Medality Medical is developing a surgical device and technique to extract fat located inside the abdomen (visceral fat) to reverse Type-2 diabetes (which can lead to heart attack, stroke, blindness, kidney failure, amputation – and death).

Diabetes: A worldwide epidemic

According to the journal of Clinical Diabetes and Endocrinology, diabetes is likely the largest epidemic in human history.  It is a global epidemic[1] with 425M people currently with this disease (9% of adult population), 352M have pre-diabetes (another 7% of adult population). In the US alone, the Center for Disease Control and Prevention (CDC) estimated that 23.1 million[2] people had diagnosed diabetes in 2015. In a recent study among a large group of US Type-2 diabetes patients, where access to therapy is at the highest level, 44% had discontinued their diabetes medications, altogether, at 6 months[3] – the drug therapy necessary to reduce the potential for long-term complications and death!  A straightforward surgical alternative may provide a valuable option to address this global epidemic.

[1] International Diabetes Federation. IDF Diabetes Atlas, 8th edition, 2017, Brussels, Belgium: http://www.diabetesatlas.org 
[2] https://www.cdc.gov/diabetes/data/statistics-report/index.html
[3] Evaluation of Treatment Persistence in Individuals with Type 2 Diabetes in a Real-World Setting; WILLIAM T. CEFALU et. al. Diabetes 2018 Jul; 67(Supplement 1): -. https://doi.org/10.2337/db18-135-OR

Our Technology

Medality Medical’s T2D-1 Visceral Fat Extraction System utilizes the unique, patented Tissue Liquefaction Technology (TLT) to apply a stream of warmed, low-pressurized and pulsed saline solution to liquefy the visceral fat tissue; while leaving non-fat tissue unharmed. The visceral fat tissue instantaneously liquefies inside the opening of the handheld surgical device upon exposure to the energized saline stream and the liquefied visceral fat is immediately sucked out of the abdomen and into a collection canister. The handheld surgical instrument is blunt and rounded to avoid cutting any tissue and the warm (not hot) saline stream is not capable of burning tissue. It applies “just enough energy” to transform the visceral fat from a solid to a liquid form to enable rapid extraction.

Visceral fat deposits are found mainly in the mesentery. The mesentery’s role is so important that two researchers – Dr. Calvin Coffey and Dr. Peter O’Leary suggest that the mesentery deserves to be recognized as a new human organ https://youtu.be/ru2--3NHQiE. Fat deposit in the mesentery also called mesenteric fat has been shown to play an important role in diseases such as type 2 diabetes, metabolic syndrome and cardiovascular disease.

Our Results

The unique T2D-1 Visceral Fat Removal System and associated surgical procedure has been successfully used in obese baboons to reverse insulin resistance that leads to Type-2 diabetes:

  • The surgical procedures were uneventful and successful​
  • Post-procedure all baboons experienced a reversal of their insulin resistance (they also lost excess weight - an average 12% of their overall body weight reduction over a 6-week time period.)
  • These results have been published in the Surgery for Obesity and Related Disease Journal (SOARD). https://www.soard.org/article/S1550-7289(18)30127-8/abstract